Research Interests:
Prof. Kossatz’s research interests involve the development and clinical translation of molecular imaging tools for improved tumor detection, intraoperative delineation, treatment and monitoring with the long-term goal to improve outcome and survival for patients. My research strategy involves investigating fluorescent and nuclear imaging probes for their suitability in molecular imaging applications and translation. This includes preclinical (in vitro and in vivo) studies, in-depth work with human biospecimens as well as implementation of early phase clinical studies. Among many promising biomarkers, fluorescent- and radiolabeled PARP inhibitors have been a specific research focus for applications ranging from brain tumor imaging and therapy to early detection and intraoperative guidance of oral and esophageal cancer.