Going Nuclear: Innovative Radiochemistry and Radiotracers

Categories: Materials, New Chemistry
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Course Content

A general approach to reduce off-target radioactivity in vivo via Tetrazine-Knock-Out (TKO)

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  • A general approach to reduce off-target radioactivity in vivo via Tetrazine-Knock-Out (TKO)
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Labeling Carbon-11 Tracers on FASTLab Using Resin, Loop, or Reactor Methods

Bringing radiochemistry into the data-science age: Using “Design of Experiments” (DoE), response surface modeling, and high-throughput radiochemistry to accelerate novel radiopharmaceutical discovery and development.

Simultaneous chemoenzymatic radiosyntheses of α-1,4 linked oligosaccharides from [18F]FDG using maltose/ maltodextrin phosphorylases.

Fluorine-18 labelled muramic acid derivatives for imaging bacterial infection

A Sweet Escape: [18F]4-Fluorodeoxytagatose resists metabolic trapping, in opposition to its stereoisomer [18F]4-fluorodeoxyfructose.

Developing a novel 18F-labeled bisphosphonate probe for PET imaging