Over the last few decades, immunotherapy has become an important part of treating some types of cancer. Many novel types of immunotherapies are under development and several have recently received FDA approval. Some of the challenges in advancing immunotherapies include patient stratification and monitoring therapeutic response. Traditional methods of monitoring treatment response are limited in their ability to provide tumor-specific information being qualitative tests that detect mainly morphologic tissue changes and thus have limited success. Noninvasive detection of immune imaging biomarkers for guidance and monitoring of immunotherapy are therefore critical. We believe that molecular imaging will play a critical role in aiding to address some of the current challenges and expedite the development of such treatments.
The Role of Molecular Imaging in Cell and Immune Therapies
Discover molecular imaging’s role in preclinical and clinical settings to track immune cells, monitor progression of immune response, and improve patient safety. Learn about the WMIS Immune Cell and Immune Therapies Interest Group.
Introduction to Imaging in Immunotherapy
Vladimir Ponomarev, MD, PhD, Faculty Member, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York
Gilbert Fruhwirth, PhD, Associate Professor in Imaging Biology, King’s College, London
Lidsay Lim, PhD, Postdoctoral Research Associate in Cancer Imaging, King’s College, London
Article:
Advancing Immune and Cell-Based Therapies Through Imaging
Vladimir Ponomarev, Department of Radiology, Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA