Recent developments in immunology and biotechnology have led to an increasing number of clinically available cellular and immune-therapies that require administration of biologics and cells of different origins. These therapies are based on novel immunologically active drugs and the ex-vivo manipulation of different therapeutically useful cell types (stem cells, lineage progenitors, mesenchymal cells, lymphocytes, dendritic cells, etc.) followed by local or systemic administration to patients. A promising role of cellular and immunotherapies in treatments of various diseases is reflected by the constantly growing number of clinical trials.
Until recently, immunostaining of whole-body slices of small animals was the most straightforward, reliable, and traditional approach used for assessing the efficacy of immunotherapeutics. However, the invasive nature of classical pathology precludes the repetitive monitoring of immune response in the same animal over time. Methods for non-invasive and repetitive evaluation of trafficking, homing, tumor targeting, differentiation, and persistence of immune and other cells and respective drugs would significantly aid the development of cellular and immunotherapeutic approaches and facilitate their implementation in the clinic.
WMIS invites you to find your place to grow, collaborate and make a difference – join the ICIT Interest Group today.
Members: Interest Groups are open to current WMIS Members. There is an annual Interest Group membership fee of $20 which is requested to help offset administrative costs. To join an interest group, please click the button below.
If you are not a current WMIS member, please click the button below and create a new profile to join WMIS and join interest groups.
To foster collaboration between imaging and immunology disciplines aimed at implementing molecular imaging in cell-based and molecular immunotherapy development and use.
The Imaging in Cell and Immune Therapies (ICIT) Interest Group:
- provides a platform for researchers interested in visualizing and quantifying immune responses as part of basic and/or translational research;
- encourages and educates next-generation researchers in imaging immune system/responses;
- establishes global cooperation to develop, advance, and standardize imaging methods to quantify immune responses;
- connects academic and industry research to advance clinical application of molecular imaging in immunotherapy.
Our mission is aligned with the WMIS goal of accelerating the global growth of molecular imaging in academic institutions and industry.